Calcitonin gene-related peptide immunoreactivity in chronic human spinal cord injury

Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species.

Calcitonin gene-related peptide (CGRP) immunoreactivity was found throughout the entire spinal cord of man, marmoset, horse, pig, cat, guinea pig, mouse, rat, and frog. CGRP-immunoreactive fibers were most concentrated in the dorsal horn. In the ventral horn of some species large immunoreactive cells, tentatively characterized as motoneurons, were present. Pretreatment of rats with colchicine e...

Calcitonin gene-related peptide in rat spinal cord motoneurons: subcellular distribution and changes induced by axotomy.

Using light and electron microscopy, a study has been made of the changes of calcitonin gene-related peptide-like immunoreactivity in rat lumbar spinal cord motoneurons during cell body response to sciatic nerve injury. At light microscopy level, calcitonin gene-related peptide-like immunoreactivity was evaluated using an indirect immunofluorescence technique combined with Fast Blue retrograde ...

Calcitonin gene related peptide.

Comparison between Brain Natriuretic Peptide and Calcitonin Gene Related Peptide in Children with Dilated Cardiomyopathy

Background: Dilated cardiomyopathy (DCM) is revealed with the left ventricular dilatation and systolic dysfunction. This study was performed to determine the level of Calcitonin Gene Related Peptide (CGRP) and Brain Natriuretic Peptide (BNP) in children with dilated cardiomyopathy and controls and comparison of these two biomarkers in patients. Materials and Methods: This case-control study was...

Calcitonin Gene–Related Peptide and Thermal Injury: Review of Literature

The aim of this review article is to report about the anti-inflammatory properties of calcitonin gene-related peptide (CGRP) in burns. CGRP is a 37-amino acid neuropeptide, primarily released from sensory nerves and is well known as the most potent and long-lasting microvascular vasodilator in vitro and hypotensive agents in vivo.A wide range of proinflammatory stimuli can induce the release of...